ChloroquineV1, Main, Exploration, bibRecord, 002853

Interstitial lung disease in children--a report of four cases.

Identifieur interne : 002853 ( Main/Exploration ); précédent : 002852; suivant : 002854

Interstitial lung disease in children--a report of four cases.

Auteurs : M Z Norzila ; B H Azizi ; C T Deng ; A. Zulfiqar

Source :

The Medical journal of Malaysia [ 0300-5283 ] ; 1997.

RBID : pubmed:10968122

Descripteurs français

KwdFr :
- Femelle, Humains, Mâle, Nourrisson, Nouveau-né, Pneumopathies interstitielles (diagnostic), Pneumopathies interstitielles (traitement médicamenteux).
MESH :
- diagnostic : Pneumopathies interstitielles.
- traitement médicamenteux : Pneumopathies interstitielles.
- Femelle, Humains, Mâle, Nourrisson, Nouveau-né.

English descriptors

KwdEn :
- Female, Humans, Infant, Infant, Newborn, Lung Diseases, Interstitial (diagnosis), Lung Diseases, Interstitial (drug therapy), Male.
MESH :
- diagnosis : Lung Diseases, Interstitial.
- drug therapy : Lung Diseases, Interstitial.
- Female, Humans, Infant, Infant, Newborn, Male.

Abstract

Interstitial lung disease (ILD) is very rare in children. In the majority of cases the aetiology is unknown. Very little is known about the clinical course of this condition in children. Prognosis may be influenced by sex, age of onset of symptoms, radiographic features, presence of right ventricular hypertrophy and histopathology. We report our experience in managing four children with interstitial lung disease. All these children presented in early infancy with cough, respiratory distress, cyanosis and failure to thrive. Three of these children had finger clubbing and right ventricular hypertrophy. All patients received oral steroids. Chloroquine was added in two patients who showed no response. A trial of oral cyclophosphamide was started in one patient who failed with both drugs. One child is oxygen independent while another is on home oxygen therapy. The other two patients eventually died.

PubMed: 10968122

Affiliations:

Le document en format XML

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<author><name sortKey="Norzila, M Z" sort="Norzila, M Z" uniqKey="Norzila M" first="M Z" last="Norzila">M Z Norzila</name>
<affiliation><nlm:affiliation>Institut Pediatrik, Hospital Kuala Lumpur.</nlm:affiliation>
<wicri:noCountry code="subField">Hospital Kuala Lumpur</wicri:noCountry>
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<author><name sortKey="Azizi, B H" sort="Azizi, B H" uniqKey="Azizi B" first="B H" last="Azizi">B H Azizi</name>
</author>
<author><name sortKey="Deng, C T" sort="Deng, C T" uniqKey="Deng C" first="C T" last="Deng">C T Deng</name>
</author>
<author><name sortKey="Zulfiqar, A" sort="Zulfiqar, A" uniqKey="Zulfiqar A" first="A" last="Zulfiqar">A. Zulfiqar</name>
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<series><title level="j">The Medical journal of Malaysia</title>
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<term>Lung Diseases, Interstitial (drug therapy)</term>
<term>Male</term>
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<keywords scheme="KwdFr" xml:lang="fr"><term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Nourrisson</term>
<term>Nouveau-né</term>
<term>Pneumopathies interstitielles (diagnostic)</term>
<term>Pneumopathies interstitielles (traitement médicamenteux)</term>
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<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Lung Diseases, Interstitial</term>
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<term>Humans</term>
<term>Infant</term>
<term>Infant, Newborn</term>
<term>Male</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Femelle</term>
<term>Humains</term>
<term>Mâle</term>
<term>Nourrisson</term>
<term>Nouveau-né</term>
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<front><div type="abstract" xml:lang="en">Interstitial lung disease (ILD) is very rare in children. In the majority of cases the aetiology is unknown. Very little is known about the clinical course of this condition in children. Prognosis may be influenced by sex, age of onset of symptoms, radiographic features, presence of right ventricular hypertrophy and histopathology. We report our experience in managing four children with interstitial lung disease. All these children presented in early infancy with cough, respiratory distress, cyanosis and failure to thrive. Three of these children had finger clubbing and right ventricular hypertrophy. All patients received oral steroids. Chloroquine was added in two patients who showed no response. A trial of oral cyclophosphamide was started in one patient who failed with both drugs. One child is oxygen independent while another is on home oxygen therapy. The other two patients eventually died.</div>
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<name sortKey="Norzila, M Z" sort="Norzila, M Z" uniqKey="Norzila M" first="M Z" last="Norzila">M Z Norzila</name>
<name sortKey="Zulfiqar, A" sort="Zulfiqar, A" uniqKey="Zulfiqar A" first="A" last="Zulfiqar">A. Zulfiqar</name>
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Serveur d'exploration Chloroquine

Interstitial lung disease in children--a report of four cases.

Interstitial lung disease in children--a report of four cases.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

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